The Buffalo Bills enter Sunday Night Football against the New England Patriots facing a tough blow to their secondary. On Saturday, the team placed promising rookie cornerback Dorian Strong on Injured Reserve with a neck injury, sidelining him for at least four weeks. Strong, a sixth-round pick who began the season as a starter opposite Christian Benford, had logged 10 tackles before the injury and will be eligible to return in Week 10. The loss further tests Buffalo's depth at corner after veteran Tre'Davious White's earlier groin setback.
Despite the defensive uncertainty, Buffalo remains a heavy favorite for this primetime AFC East clash at Highmark Stadium. Josh Allen and running back James Cook headline an offense that has averaged nearly 30 points per game, while rookie quarterback Drake Maye leads a Patriots team eager to find rhythm on the road. Oddsmakers currently list the Bills as 8.5-point favorites, with the total set at 49.5, hinting at a potential high-scoring affair in Orchard Park.
Following Strong's injury designation, Dimers' analysts updated their projections for the Patriots vs. Bills matchup, rerunning 10,000 simulations to account for the defensive shakeup. The result? A new data-driven betting preview highlighting Buffalo's 77% win probability and key player prop edges heading into Sunday night's showdown.
Utilize the interactive widget below to view the latest spread, over/under, and moneyline odds and probabilities for the Patriots-Bills matchup at Highmark Stadium.
This prediction and best bet for Sunday's NFL matchup between the Patriots and Bills is from Dimers.com, a reliable source for sports betting predictions.
Check out all the important details on today's game, as well as the best odds sourced from the top sportsbooks in the country.
Key information on the Patriots vs. Bills matchup, including where the game is and what time it kicks off.
The latest and best odds for the NFL showdown between the Patriots and Bills.
The odds and lines featured here are the best available from selected sports betting sites at the time of publication and are subject to change.
Fans of both teams can unlock betting bonuses with the NFL Week 5 betting promos from DraftKings, BetMGM, and FanDuel, while Bet365's $200 sign-up offer has emerged as the most popular SNF betting deal among local fans in New Jersey.
Utilizing state-of-the-art data analysis and machine learning, the experts at Dimers have executed 10,000 simulations of Sunday's Patriots vs. Bills game.
According to Dimers' renowned predictive analytics model, the Bills are more likely to beat the Patriots at Highmark Stadium. This prediction is based on the model giving the Bills a 77% chance of winning the game.
Furthermore, Dimers predicts that the bookmakers have gotten it right and the Patriots and Bills each have a 50% chance of covering the spread, while the 49.5-point over/under is also considered an equal 50-50 chance of hitting.
As always, these predictions and probabilities are accurate at the time of publication but are subject to potential changes.
Our top pick for the Patriots vs. Bills Week 5 NFL matchup is to bet on the Patriots moneyline (+350).
This betting advice is formulated through detailed modeling and valuable betting intelligence, designed to deliver you the best possible plays.
While the Bills are more likely to win the game, according to Dimers, taking the Patriots moneyline is the best option due to the edge found when comparing Dimers' data-driven probabilities to the betting odds.
Dimers' predicted final score for the New England vs. Buffalo game on Sunday has the Bills winning 29-20.
This expert prediction is based on each team's average score following 10,000 game simulations, offering a glimpse into the potential outcome.
NFL props are an enjoyable way to wager on Sunday's game without necessarily betting on its outcome.
This article features the most likely first and anytime touchdown scorers for the Patriots and Bills, along with projected player stats.
Get ready for Sunday's matchup between the Patriots and Bills in Week 5 of the NFL season at Highmark Stadium, which is scheduled to start at 8:20 p.m. ET. We emphasize that all of the NFL predictions and NFL best bets in this preview are derived from 10,000 data-driven simulations of the Patriots vs. Bills matchup, and they are correct at the time of publication. They aim to help you make better decisions when placing bets at online sportsbooks.
Please note that when engaging in online betting, it is important to exercise responsible gambling practices and consult trustworthy sources for accurate and up-to-date information.